Effects of long-term monotherapy with enalapril, metoprolol, and digoxin on the progression of left ventricular dysfunction and dilation in dogs with reduced ejection …

HN Sabbah, H Shimoyama, T Kono, RC Gupta… - Circulation, 1994 - Am Heart Assoc
BACKGROUND Recent clinical trials have suggested that therapy with angiotensin-
converting enzyme inhibitors in asymptomatic patients with reduced left ventricular (LV)
function can significantly reduce the incidence of congestive heart failure compared with
patients receiving placebo. In the present study, we examined the effects of long-term
monotherapy with enalapril, metoprolol, and digoxin on the progression of LV systolic
dysfunction and LV chamber enlargement in dogs with reduced LV ejection fraction (EF) …

[PDF][PDF] Effects of Long-term Monotherapy With Enalapril, Metoprolol, and Digoxin on the Progression of Left Ventricular Dysfunction and Dilation in Dogs With Reduced …

VG Sharov, B Levine, S Goldstein - 1994 - Citeseer
Background Recent clinical trials have suggested thatther-apy with angiotensin-converting
enzyme inhibitors in asymp-tomatic patients with reduced left ventricular (LV) function can
significantly reduce theincidence of congestive heart failure compared with patients
receiving placebo. In the present study, we examined the effects of long-term monother-apy
with enalapril, metoprolol, and digoxin on the progression of LV systolic dysfunction and LV
chamber enlargement in dogs with reduced LV ejection fraction (EF). Methods and Results …
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